Organization and activation of the human brain sexual differentiation of the brain brings about permanent changes in brain structures and functions via interaction . In the twentieth century the dominant model of sexual differentiation stated that genetic sex xx versus xy causes differentiation of the gonads which . As outlined in prior chapters gonadal hormones have powerful influences on sexual differentiation of brain and behavior in a wide range of mammals. As sexual differentiation of the brain takes place at a much later stage in development than sexual differentiation of the genitals
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